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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TARDBP
All Species:
9.09
Human Site:
Y77
Identified Species:
25
UniProt:
Q13148
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13148
NP_031401.1
414
44740
Y77
N
L
V
Y
V
V
N
Y
P
K
D
N
K
R
K
Chimpanzee
Pan troglodytes
XP_001135126
357
37996
F35
L
S
T
V
T
A
Q
F
P
G
A
C
G
L
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q921F2
414
44529
Y77
N
L
V
Y
V
V
N
Y
P
K
D
N
K
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515386
295
33249
Chicken
Gallus gallus
Q5ZLN5
414
44571
Y77
N
L
V
Y
V
V
N
Y
P
K
D
N
K
R
K
Frog
Xenopus laevis
Q6NU14
291
32937
Zebra Danio
Brachydanio rerio
NP_958884
412
44409
V83
V
N
Y
P
K
E
T
V
L
P
D
N
K
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392590
466
50438
K79
I
Y
F
C
V
F
P
K
E
N
K
R
K
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
P132
T
M
S
Q
F
Q
Q
P
S
S
Q
S
P
P
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
N.A.
N.A.
N.A.
96.1
N.A.
N.A.
66.6
95.1
22.7
76
N.A.
N.A.
49.5
N.A.
N.A.
Protein Similarity:
100
86.2
N.A.
N.A.
N.A.
98.7
N.A.
N.A.
69.5
97.3
38.4
86.4
N.A.
N.A.
63
N.A.
N.A.
P-Site Identity:
100
6.6
N.A.
N.A.
N.A.
100
N.A.
N.A.
0
100
0
33.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
20
N.A.
N.A.
N.A.
100
N.A.
N.A.
0
100
0
33.3
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
45
0
0
0
12
% D
% Glu:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% E
% Phe:
0
0
12
0
12
12
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
12
0
0
12
0
34
12
0
56
0
45
% K
% Leu:
12
34
0
0
0
0
0
0
12
0
0
0
0
12
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
34
12
0
0
0
0
34
0
0
12
0
45
0
0
0
% N
% Pro:
0
0
0
12
0
0
12
12
45
12
0
0
12
12
0
% P
% Gln:
0
0
0
12
0
12
23
0
0
0
12
0
0
0
12
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
12
0
45
12
% R
% Ser:
0
12
12
0
0
0
0
0
12
12
0
12
0
12
0
% S
% Thr:
12
0
12
0
12
0
12
0
0
0
0
0
0
0
0
% T
% Val:
12
0
34
12
45
34
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
12
34
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _